Impact of androgen-induced oxidative stress on hypertension in male SHR by
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CALL FOR PAPERS Sex Differences in Renal and Cardiovascular Function: Physiology and Pathophysiology Impact of androgen-induced oxidative stress on hypertension in male SHR
Iliescu R, Cucchiarelli VE, Yanes LL, Iles JW, Reckelhoff JF. Impact of androgen-induced oxidative stress on hypertension in male SHR. Am J Physiol Regul Integr Comp Physiol 292: R731–R735, 2007. First published July 20, 2006; doi:10.1152/ajpregu.00353.2006.—Men have higher blood pressure than women, and androgens and oxidative stress have been implicated as playing roles in this sexual dimorph...
متن کاملImpact of androgen-induced oxidative stress on hypertension in male SHR.
Men have higher blood pressure than women, and androgens and oxidative stress have been implicated as playing roles in this sexual dimorphism. The spontaneously hypertensive rat (SHR) is an animal model of both androgen- and oxidative stress-mediated hypertension. Therefore, the present studies were performed to test the hypothesis that androgens cause hypertension in SHR in part by stimulating...
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NADPH oxidase has been implicated in ANG II-induced oxidative stress and hypertension in males; however, the contribution of oxidative stress to ANG II hypertension in females is unknown. In the present study, we tested the hypothesis that greater antioxidant capacity in female spontaneously hypertensive rats (SHR) blunts ANG II-induced oxidative stress and hypertension relative to males. Whole...
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